Researchers identify inhibitors of the SARS-CoV-2 Nsp14 N7-methyltransferase

Study: Structure-based discovery of inhibitors of the SARS-CoV-2 Nsp14 N7-methyltransferase. Image Credit: MaciejForyszewski/Shutterstock

A recent study posted to bioRxiv* identified inhibitors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 14 (Nsp14). Study: Structure-based discovery of inhibitors of the SARS-CoV-2 Nsp14 N7-methyltransferase. Image Credit: MaciejForyszewski/Shutterstock background Viral proteins like the papain-like protease and methyltransferases such as the Nsp14 are crucial for SARS-CoV-2 virulence and seem attractive candidates … Read more